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CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment

机译：CDC25a蛋白稳定性代表了人类乳腺癌中HER2信号传导的先前未被认识的靶点：对曲妥珠单抗治疗中潜在临床相关性的意义

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Emanuela Brunetto; Anna Maria Ferrara; Francesca Rampoldi; Anna Talarico; Elena DalCin; Greta Grassini; Lorenzo Spagnuolo; Isabella Sassi; Antonella Ferro; Lucia Veronica Cuorvo; Mattia Barbareschi; Sara Piccinin; Roberta Maestro; Lorenza Pecciarini; Claudio Doglioni; Maria Giulia Cangi;
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1. CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment [J] . Emanuela Brunetto, Anna Maria Ferrara, Francesca Rampoldi, Neoplasia: an international journal for oncology research . 2013,第6期

机译：CDC25A蛋白质稳定性代表了人乳腺癌中先前未被识别的HER2信号传导的靶标：在曲妥珠单抗治疗中的潜在临床相关性的含义
2. Population pharmacokinetics of trastuzumab emtansine (T-DM1), a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer: Clinical implications of the effect of covariates [J] . LuD., GirishS., GaoY., Cancer chemotherapy and pharmacology. . 2014,第2期

机译：曲妥珠单抗Emtansine（T-DM1）（一种靶向HER2的抗体-药物结合物）在HER2阳性转移性乳腺癌患者中的群体药代动力学：协变量作用的临床意义
3. Clinical implications of pathophysiological and demographic covariates on the population pharmacokinetics of trastuzumab emtansine, a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer [J] . GuptaM., LorussoP.M., WangB., The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2012,第5期

机译：病理生理和人口统计学协变量对HER2阳性转移性乳腺癌患者曲妥珠单抗Emtansine（一种靶向HER2的抗体-药物结合物）的群体药代动力学的临床意义
4. Modulating trastuzumab density and magnetic targeting duration of pH-sensitive magnetic nanocarriers for synergistically targeting to HER2-positive breast cancer [C] . San-Yuan Chen, Chih-Sheng Chiang World biomaterials congress . 2016

机译：调节曲妥珠单抗密度和pH敏感的磁性纳米载体的磁性靶向持续时间以协同靶向HER2阳性乳腺癌
5. Somatostatin receptor-mediated negative modulation of HER2 phosphorylation, signaling, and in vitro invasive potential in breast cancer [D] . Vaidya, Kedar S. 2005

机译：生长抑素受体介导的HER2磷酸化，信号转导和体外浸润潜能在乳腺癌中的负调控
6. CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment [O] . Emanuela Brunetto, Anna Maria Ferrara, Francesca Rampoldi, 2013

机译：CDC25A蛋白稳定性代表人类乳腺癌中HER2信号的一个先前无法识别的靶标：曲妥珠单抗治疗中潜在的临床意义
7. CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment [O] . Brunetto Emanuela, Ferrara Anna Maria, Rampoldi Francesca, 2013

机译：CDC25A蛋白稳定性代表人类乳腺癌中HER2信号的一个先前无法识别的靶标：曲妥珠单抗治疗中潜在的临床意义
8. Targeting SIAH E3 Ligase Downstream of the HER2/Neu/RAS Signaling Pathway to Block Tumorigenesis and Metastasis of Highly Invasive Human Breast Cancer. [R] . Tang, A. H. 2012

机译：针对HER2 / Neu / Ras信号通路下游的sIaH E3连接酶阻断高侵袭性人乳腺癌的肿瘤发生和转移。

CDC25A Protein Stability Represents a Previously Unrecognized Target of HER2 Signaling in Human Breast Cancer: Implication for a Potential Clinical Relevance in Trastuzumab Treatment

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